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[DOI] [PubMed] [Google Scholar] 98.Binolfi A, Rodriguez EE, Valensin D, DAmelio N, Ippoliti E, Obal G, et al

Freeze-thaw cycles rupture membranes through the expansion of ice crystals during the freezing phase, thereby increasing membrane permeability upon thawing [178]

doi:10.1126/science.1093941

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Johns Hopkins neuroimaging studies (2024-2025) reveal measurable white matter abnormalities and persistent neuroinflammation in post-treatment Lyme disease patientsfindings that mirror those seen in persistent post-concussion syndrome