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Fourth, exploring the interactions between ferroptosis, cuproptosis, and other cell death pathways (such as apoptosis, autophagy, and necroptosis) may reveal more complex cell death regulatory networks and offer new ideas for overcoming multidrug resistance

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Thus, the APAP-CYS and PAP-CYS conjugates were synthesized, purified and used for the treatment in human kidney HK-2 cells

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To monitor the severity of arthritis, each paw was scored on a scale of 04 based on the degree of erythema and swelling: 0 indicated no signs, while 4 represented complete ankylosis and inability to bend the ankle