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First: PI3K/Akt/mTOR, which drives protein synthesis, glucose uptake (via GLUT4 translocation), and anti-apoptotic signaling (particularly relevant in muscle and neuronal tissue)

Muscle Preservation After 35 After 35, muscle loss accelerates in women partly because GH is a key signal for protein synthesis and lean tissue maintenance

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doi: 10.1016/j.abb.2023.109622 54 JiaqiLSiqingHQinWdiZBeiZJialinY