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Description

The NADPH oxidase (NOX) family also plays a central role in hepatic ROS generation [112]

CHRIS MASTERJOHN: Im not sure

Nature 599, 692696

ROS-mediated cell signaling As outlined above, ROS have origin from two main sources: mitochondrial oxidative metabolism and processes of cellular response to xenobiotics, bacteria, and cytokines during which ROS are formed as a part of either signal transduction pathways or a cellular defense mechanism (Finkel 2011)