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This guideline was developed by the Guidelines and Protocols Advisory Committee in collaboration with the Provincial Laboratory Medicine Services, and adopted under the Medical Services Act and the Laboratory Services Act

Di Giacomo TB , Valente NYS and Nico MMS (2009) Chloroquine induced hair depigmentation

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At the infection site, the low intracellular calcium concentration triggers the release mechanism of the nanocrystals, allowing the drug to be directly released inside the cells, thereby avoiding systemic tissue damage caused by Amphotericin B (Boulware et al., 2023)

Another common preclinical model involves using chemically induced damage, such as oxidative stress or inflammation, to test the peptides potential in mitigating cellular damage