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Twelve days after the injection of m 5 C + -mRNA-LCP, tumor volume was reduced by 80% and 90% compared to canonical mRNA-LCP and non-vaccinated animals, respectively

doi: 10.1016/S0002-9440(10)61135-2

Transferred intratumoral OT-1 GPX4 cKO CD8 + T cells displayed a similar exhausted-like phenotype (expressing PD-1 and Lag-3) (Supplemental Figure 1M) but an increased stem-like phenotype (expressing Ly108 and CD69) (Supplemental Figure 1N) compared with control CD8 + T cells

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